Allelic Based Gene-Gene Interaction in Case-Control Studies
نویسندگان
چکیده
منابع مشابه
Allelic based gene-gene interaction in case-control studies.
In case-control studies identifying disease susceptibility loci, it has been shown that the interaction caused by multiple single nucleotide polymorphisms (SNPs) within a gene as well as by SNPs at unlinked genes plays an important role in influencing risk of a disease. A novel statistical approach is proposed to detect gene-gene interactions at the allelic level contributing to a disease trait...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2010
ISSN: 1423-0062,0001-5652
DOI: 10.1159/000243150